This reference on veterinary embryology covers general embryology, i.e. the development from the formation of the gametes over fertilization and initial embryogenesis up to the stage where organ formation is initiated, and special embryology, i.e. the development of the organ systems. Moreover, the book also includes a section on teratology, one on assisted reproductive technologies and one on veterinary and societal aspects. Written with the veterinary student in mind, this textbook is written in an accessible style with high quality colour illustrations and line drawings.
Key Features
- Succinct and accessible
- 300 high-quality colour illustrations
- Written for undergraduates and invaluable for graduates wishing to brush up
Author Information
By Poul Hyttel, DVM, PhD, DVSc, Professor, Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark; Fred Sinowatz, Dr.med vet., Dr.med, Dr.habil, Professor, Institute of Veterinary Anatomy, Histology and Embryology, LMU Munich, Germany; Morten Vejlsted, DVM, PhD, Assistant Professor, Department of Large Animal Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark and Keith Betteridge, BVSc, MVSc, PhD, FRCVS, University Professor Emeritus, Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Ontario, Canada
CONTENTS
INTRODUCTION & GENERAL PRINCIPLES
1 Cellular and Molecular Mechanisms of Morphogenesis
• Cell proliferation: Cell cycle, differentiation, regulation
• Cell demise: Apoptosis
• Cytoskeleton/Extracellular Matrix/Cell-Matrix interactions
• Morphogenesis & Patterning
2 Comparative Gestation
• Distinctions of the Early Embryo, Embryonic and Fetal Periods of Gestation
• Species Variations Effecting Gestation Length: Companion, Domestic, Wildlife and Laboratory Animals
• Reproductive Cycles: Hormones, Estrous, Organs, Seasonal
• Fecundity: Survival Strategies, Conception Rates
DIFFERENTIATION OF GERM LAYERS
3. Gametogenesis
• Mitosis/Meiosis
• Oogenesis
• Spermatogenesis
• Veterinary Clinical Applications/Cases
4. Fertilization
• Acrosome Reaction
• Sperm-Zona Pellucida Interactions
• Gamete Fusion
• Blocks to Polyspermy
• Syngamy and Embryo Activation
• Veterinary Clinical Applications/Cases
5. Embryo Cleavage and Blastulation
• Polarity, Compaction and Cavitation
• Embryonic Disc, Primitive Streak and Formation of the Bilaminar Embryo
• Veterinary Clinical Applications/Cases
6. Gastrulation, Body Folding and Coelom Formation
• Notocord, Neural Tube and Segmentation
• Differentiation of Ectoderm, Mesoderm and Endoderm
• Body Folding, Coelom Formation and Lung Development
• Veterinary Clinical Applications/Cases
7. Development of the Peripheral Nervous System
• Spinal Cord and Motor/Sensory Innervation
• Somite Development
8. Comparative Placentation
• Extraembryonic Membranes: Amnion, Yolk Sac, Allantois, Chorion
• Placental Strategies: Choriovitelline, Chorioallantoic
• Species Variations
• Veterinary Clinical Applications/Cases
SYSTEMS DEVELOPMENT
9. Development of the Limbs
• Limb Bud Formation
• Apical Ectodermal Ridge
• Development of the Appendicular Skeleton, Musculature, Vasculature and Innervation
• Differentiation of Distal Appendages: Digit Formation
• Veterinary Clinical Applications/Cases
10. Development of the Heart
• Primitive Heart Tube Formation
• Development of Heart Chambers and Valves
• Development of the Conduction System
• Veterinary Clinical Applications/Cases
11. Development of the Vascular System
• Formation of the Aortic Arches and the Arterial System
• Development of the Vitelline, Umbilical and Cardinal Venous System
• The Coronary Vasculature
• Circulatory changes at Parturition
• Veterinary Clinical Applications/Cases
12. Development of the Gastrointestinal System
• The Enteric Canal
• Stomach, Pancreas, Liver and Spleen
• Development of Peritoneum and Formation of Mesenteries
• Rotation and Fixation of the Midgut
• Differentiation of the Large Bowel
• Septation and Differentiation of the Cloaca
• Veterinary Clinical Applications/Cases
13. Development of the Urogenital System
• Pronephros Differentiation
• Development of the Mesonephric and Metanephric Kidneys
• Urogenital Ridge and Gonad Development
• Development of the Urogentital Duct Systems and External Genitalia
• Veterinary Clinical Applications/Cases
14. Development of the Head and Neck
• Development of the Skull and Vertebrae
• Differentiation of Pharyngeal Arch Structures and Pouch Derivatives
• Development of the Palate, Tongue and Pituitary
• Development of Facial Structures
• Veterinary Clinical Applications/Cases
15. Development of the Brain and Cranial Nerves
• Regional Differentiation and Functional Relationships
• Development of the Ventricular System
• Development and Function of the Cranial Nerves
• Veterinary Clinical Applications/Cases
16. Development of the Eyes and Ears
• Formation of the Ear
• Formation of the Eye
• Veterinary Clinical Applications/Cases
17. Development of the Integumentary System
• Differentiation of the Epidermis and Dermis
• Development of Epidermal Glands including Mammary Glands
• Formation of Hair and Teeth
• Veterinary Clinical Applications/Cases
CLINICAL AND APPLIED SYSTEMS
18. Teratology
• Genetic & Congenital
• Critical Periods & Teratogenic Agents
• Maternal/Fetal Interactions
• Specie-Specific Manifestations
19. Assisted Reproductive Technologies
• Artificial Insemination and Embryo/Gamete Transfer (ET,GIFT, ZIFT, etc)
• Cryopreservation of Germplasm
• In Vitro Maturation, Fertilization and Embryo Production
• Embryo Micromanipulation: Splitting, ICSI, Transgenics, Embryonic Stem Cells/ Chimeras, Cloning
20. Applied Embryology: Veterinary and Societal Issues
• The Role of the Veterinarian
• Contemporary Issues
Additional Reading - References
Glossary
Index
"However, this work remains an excellent reference & study handbook for which many embryologists and veterinary students have waited so long since the book by Noden and de Lahunta went out of press. More than the work of McGeady et al., the Essentials of Domestic Animal Embryology by Hyttel et al. is a worthy successor of the latter. It is contemporary in all fields: its approach of the subject, its style and volume, the language, the huge amount of illustrations... and I'm sure it will serve as a reference handbook for many years." Pieter Cornillie Lecturer in Veterinary Embryology at Ghent University May 2010
"The quality of illustrations in the book is outstanding, ranging from simple diagrammatic drawings to full-colour histology slides and photographs of embryos and fetuses...Each chapter is clearly written and successfully combines basic information, which would be necessary if one had no prior knowledge of the chapter's topic, with detailed, up-to-date information of interest to those for whom the topic familiar...The authors have drawn widely on illustrations and contributions to the textprovided by colleagues with expertise in different areas, and the result is a beautifully illstrated, comprehensive book, which is surprisingly small in size and modest in price. It will be not only of use but also a joy to browse for everyone from first-year veterinary students to embryologists and reproductive specialists."
Vet Record, March 2012
