Clinical Ocular Toxicology, Drug-Induced Ocular Side Effects

Clinical Ocular Toxicology

Drug-Induced Ocular Side Effects

By Frederick T. Fraunfelder, MD, Professor, Department of Ophthalmology, Casey Eye Institute, Oregon Health Sciences University, Portland, OR, USA gregory.ginsberg.uphs.upenn.edu; (Kelly); Frederick W. Fraunfelder, Jr., MD, M.B.A, Roy E. Mason and Elizabeth Patee Mason Professor and Chair, Department of Ophthalmology, Mason Eye Institute, University of Missouri Columbia School of Medicine, Columbia, MO, USA and Wiley A. Chambers


Instructions to Users

1 Principles of Therapy, Focke Ziemssen, MD, Manfred Zierhut, MD

2 Ocular Drug Delivery and Ocular Toxicology, Frederick T. ?Fritz? Fraunfelder, MD

3 Methods to Evaluate Drug-Induced Visual Side Effects, Wiley A. Chambers, MD

4 Electrophysiology testing in Ocular Toxicology, Eberhart Zrenner, MD

5 National Registry of Drug-Induced Ocular Side Effects, Frederick W. ?Rick? Fraunfelder, MD, Frederick T. ?Fritz? Fraunfelder, MD

6 Herbal Medicines and Dietary Supplements - An Overview Frederick W. ?Rick? Fraunfelder, MD

7 Drug-Induced Ocular Side Effects

Section 1 ? Anti-Infectives

* AIDS-Related Agents * Amebicides * Antihelmintics * Antibiotics * Antifungal Agents * Antileprosy Agents * Antimalarial Agents * Antiprotozoal Agents * Antitubercular Agents

Section 2 ? Agents Affecting the Central Nervous System

* Analeptics * Anorexiants * Antianxiety Agents * Anticonvulsants * Antidepressants * Antipsychotic Agents * Psychedelic Agents * Sedatives and Hypnotics

Section 3 ? Analgesics, Narcotic Antagonists, and Agents Used to Treat Arthritis

* Agents Used to Treat Gout * Antirheumatic Agents * Mild Analgesics * Narcotic Antagonists* Strong Analgesics

Section 4 ? Agents Used in Anesthesia

* Adjuncts to Anesthesia * General Anesthesia* Local Anesthetics * Therapeutic Gases

Section 5 ? Gastrointestinal Agents

* Agents Used to Treat Acid Peptic Disorders * Antacids * Antiemetics * Antilipidemic Agents * Antispasmodics * Gastrointestinal and Urinary Tract Stimulants

Section 6 ? Cardiac, Vascular and Renal Agents

* Agents Used to Treat Migraine * Antianginal Agents * Antiarrythmic Agents * Antihypertensive Agents * Bronchodilators * Diuretics * Osmotics * Peripheral Vasodilators * Vasopressors

Section 7 ? Hormones and Agents Affecting Hormonal Mechanisms

* Adrenal Corticosteroids * Androgens * Antithyroid Agents * Erectile Dysfunction Agents * Estrogens and Progestogens * Ovulatory Agents * Thyroid Hormones

Section 8 ? Agents Affecting Blood Formation and Coagulability

* Agents Used to Treat Deficiency Anemias * Anticoagulants * Blood Substitutes

Section 9 ? Homeostatic Agents

* Agents Used to Treat Hyperglycemia

Section 10 ? Agents Used to Treat Allergic and Neuromuscular Disorders

* Agents Used to Treat Myasthenia Gravis * Antihistamines * Antiparkinsonism Agents * Cholinesterase Reactivators * Muscle Relaxants

Section 11 ? Oncolytic Agents

* Antineoplastic Agents

Section 12 ? Heavy Metal Antagonists and Miscellaneous Agents

* Agents Used to Treat Alcoholism * Calcium Regulating Agents * Chelating Agents * Diagnostic Aids * Immunosuppressants * Retinoids * Solvents * Vaccines

Section 13 ? Drugs Used in Ophthalmology

* Agents Used to Treat Age-Related Macular Degeneration * Agents Used to Treat Allergies * Agents Used to Treat Glaucoma * Antiviral Agents * Carbonic Anhydrase Inhibitors * Decongestants * Mydriatics and Cycloplegics * Neurotoxins * Ophthalmic Dyes * Ophthalmic Implants * Ophthalmic Preservatives and Antiseptics * Proteolytic Enzymes * Topical Local Anesthetics * Topical Ocular Nonsteroidal Anti-Inflammatory Drugs * Topical Osmotic Agents * Viscoelastics

8 Chemical-Induced Ocular Side Effects, Devin Gattey, MD

* Acids * Aerosals * Alcohols * Alkali * Bleaches * Detergents * Glues * Herbicides and Insecticides * Hydrocarbons * Miscellaneous

9 Herbal Medicines and Dietary Supplement-Induced Ocular Side Effects

10 Index of Side Effects

11 Index of Drug Names