Cytopathologic Diagnosis of Serous Fluids

Cytopathologic Diagnosis of Serous Fluids

By Vinod B. Shidham, MD, Professor, Director of FNAB Service and Cytopathology Fellowship Program, Medical College of Wisconsin, Milwaukee, WI; and Barbara F. Atkinson, MD, Chair and Professor, Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine, Kansas City, KS, USA

1. Introduction

2. The panorama of different faces of mesothelial cells

3. Approach to diagnostic cytopathology of serous effusions

4. Diagnostic pitfalls in effusion fluid cytology

5. Immunocytochemistry of effusion fluids: introduction to SCIP approach

6. Reactive conditions

7. Diagnostic cytopathology of peritoneal washing

8. Mesothelioma

9. Metastatic carcinoma in effusions

10. Metastaic sarcomas, melanoma, and other non-epithelial malignancies

11. Where do they come from? Evaluation of unknown primary site of origin

12. Hematolyphoid disorders

13. Flow cytometry, molecular techniques, and other special techniques

Appendix 1: Collection and processing of serous cavity fluids for cytopathologic evaluation

Appendix 2: Immunocytochemistry of effusions - processing and commonly used immunomarkers