Clinical Pharmacology, 11th Edition

Clinical Pharmacology

11th Edition

By Peter N. Bennett, MD FRCP DPMSA, Formerly Reader in Clinical Pharmacology, University of Bath, and Consultant Physician, Royal United Hospital, Bath, UK; Morris J. Brown, MA MSc FRCP FAHA FMedSci, Professor of Clinical Pharmacology, University of Cambridge; Consultant Physician, Addenbrooke?s Hospital, Cambridge; and Director of Clinical Studies, Gonville and Caius College, University of Cambridge, Cambridge, UK and Pankaj Sharma, MD PhD FRCP, Reader in Clinical Neurology at Imperial College London; Consultant Neurologist at Hammersmith Hospitals, London, UK


Section 1 General. Clinical pharmacology. Topics in drug therapy. Discovery and development of drugs. Evaluation of drugs in humans. Official regulation of medicines. Classification of drugs and naming of drugs. Section 2 From Pharmacology to Toxicology. General pharmacology. Unwanted effects of drugs: adverse reactions. Poisoning, drug overdose, antidotes. Drug abuse. Section 3 Infection and Inflammation.. Chemotherapy of infections. Antibacterial drugs. Chemotherapy of bacterial infections. Viral, fungal, protozoal and helminthis infections. Drugs for inflammation and rheumatological disease. Drugs and the skin. Section 4 Nervous System. Pain and analgesics. Anaesthesia and neuromuscular block. Psycotropic drugs. Epilepsy, parkinsonism and allied conditions. Section 5 Cardiorespiratory and Renal Systems. Cholinergic and antimuscarinic (anticholinergic) mechanisms and drugs. Adrenergic mechanisms and drugs. Arterial hypertension, angina pectoris, myocardial infarction. Cardiac arrhythmia and heart failure. Hyperlipidaemias. Kidney and urinary tract. Respiratory system. Section 6 Blood and Neoplastic Disease. Drugs and haemostasis. Cellular disorders and anaemias. Neoplastic disease and immunosuppression. Section 7 Gastrointestinal System. Oesophagus, stomach and duodenum. Intestines. Liver, biliary tract and pancreas. Section 8 Endocrine System, Metabolic Conditions. Adrenal corticosteroids, antagonists, corticotrophin. Diabetes mellitus, insulin, oral antidiabetic agents, obesity. Thyroid hormones, antithyroid drugs. Hypothalmic, pituitary and sex hormones. Vitamins, calcium, bone.