Basic and Clinical Immunology, with STUDENT CONSULT access, 2nd Edition

Basic and Clinical Immunology

2nd Edition with STUDENT CONSULT access

By Mark Peakman, MBBS, PhD, FRCPath, Professor of Immunology, King's College London; Honorary Consultant Immunologist, King's College Hospital, London, UK; and Diego Vergani, MD, PhD, FRCPath, FRCP, Professor of Liver Immunopathology, King's College London; Honorary Consultant Immunologist, King's College Hospital, London, UK


Anatomy and cells of the immune system. Innate immunity I: physical and humoral protection. Innate immunology II: cellular mechanisms. Acquired immunity: antigen receptors. The human leukocyte antigens. Cellular immune responses I: dendritic cells, macrophages and B lymphocytes. Cellular immune responses II: T lymphocytes, antigen presentation and natural killer cells. The immune response to microbes: an overview. Tolerance and mechanisms of autoimmunity. Hypersensitivity reactions and clinical allergy. Transplantation. Rheumatic diseases. Endocrine autoimmune disease. Liver diseases. Gastrointestinal diseases. Immune-mediated nephritis and vasculitis. Immune-mediated skin disease. Immune-mediated diseases of the nervous system and eye. Immunodificiency. Human immunodeficiency virus and AIDS. Immunological manifestations of haematological disease. Immune-based therapies. Immunisation.