Churchill's In Clinical Practice Series: Diabetes and The Heart

Churchill's In Clinical Practice Series: Diabetes and The Heart

By Anthony H. Barnett, MB BS, BSc (Hons), MD, FRCP, Professor of Medicine, University of Birmingham, Consultant Physician and Head of Diabetes Services Birmingham Heartlands and Solihull NHS Trust (Teaching); and Geraldine O'Gara, MB BCh, MRCGP, General Practitioner and Hospital Practitioner in Diabetes Birmingham Heartlands and Solihull NHS Trust (Teaching)


Introduction and background - scale of the problem of diabetes; reasons for exponential rise in numbers; overview of vascular complications.
Definition and epidemiology - diabetes and cardiovascular disease focus on the heart scale of the problem
Aetiology - importance of metabolic (insulin resistance) syndrome. Co-occurrence of risk factors for atherogenesis and vascular disease
Obesity
Lipids
Hypertension
Glycaemia
Smoking
Diagnosis - diabetes is a cardiovascular disease risk factor screening low threshold for investigations tools for investigation
Prevention - evidence base for treatment key clinical trials
Treatment - obesity, dyslipidaemia, hypertension, glycaemia, lifestyle advice
Future developments - emphasis on care pathways algorithmic approaches treating to target new uses for established therapies (e.g. glitazones, rapid acting insulin secretagogues)
Clinical cases
Appendices
References
Index