Pharmacology Condensed, With STUDENT CONSULT Online Access, 2nd Edition

Pharmacology Condensed

2nd Edition With STUDENT CONSULT Online Access

By Maureen M. Dale, MB, BCh, PhD, Senior Teaching Fellow, Department of Pharmacology, University of Oxford, Oxford; Honorary Lecturer, Department of Pharmacology, University College, London, UK; and Dennis G. Haylett, BSc, PhD, Senior Lecturer, Department of Pharmacology, University College, London

1 General Principles of drug action

2 Molecular aspects of drug action

3 Excitable tissues and secretory mechanisms

4 Cell proliferation and apoptosis

5 Measurement of drug action

6 Absorption and distribution of drugs

7 Drug metabolism and excretion

8 Pharmacokinetic aspects of drug action

9 The autonomic nervous system

10 Cholinergic transmission

11 Noradrenergic transmission

12 Other peripheral mediators: 5-hydroxytryptamine and purines

13 Other peripheral mediators: peptides and proteins

14 Other peripheral mediators: nitric oxide

15 Cannabinoids

16 Inflammation & anti-inflammatory drugs

17 Immune responses and immunosuppressant drugs

18 Cardiac rhythm and dysrhythmias

19 Blood pressure and hypertension

20 Cardiac blood flow, angina and myocardial infarction

21 Cardiac output and cardiac failure

22 Atheromatous disease and lipoprotein metabolism

23 Haemostasis and thrombosis

24 The haemopoietic system

25 Respiration, asthma and COPD

26 The kidney

27 The gastrointestinal tract

28 Blood sugar and diabetes

29 The anterior pituitary and the adrenal cortex

30 The thyroid

31 Bone metabolism

32 The reproductive system

33 Outline of transmission and drug action in the CNS

34 Aminoacid transmitters in the CNS

35 Other CNS transmitters

36 Neurodegenerative disorders

37 General anaesthetics

38 Anxiolytic and hypnotic drugs

39 Antipsychotic drugs

40 Drugs used in affective disorders

41 Antiepileptic drugs

42 Analgesic drugs and the control of pain

43 CNS stimulants and psychotomimetics

44 Local anaesthetics

45 Drug dependence and drug abuse

46 Cancer biology and chemotherapy

47 Antibacterial agents

48 Antiviral drugs

49 Antiprotozoal drugs

50 Antifungal and anthelminthic drugs

Appendix 1: The Schild plot and pA2

Appendix 2: The postulated action of NSAIDs on the enzymes Cyclooxygenase-1 and Cyclooxygenasox-2

Appendix 3: The pathogenesis of rheumatoid joint damage and the action of anti-rheumatoid drugs